Изворни код странице Protein geranilgeraniltransferaza tip II

{{Infobox Enzim-lat
| Name = Protein geranilgeraniltransferaza tip II
| EC_number = 2.5.1.60
| CAS_number = 135371-29-8
| IUBMB_EC_number = 2/5/1/60
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Protein geranilgeraniltransferaza tip II''' ({{EC broj-lat|2.5.1.60}}, -{''GGTaseII''}-, ''Rab geranilgeraniltransferaza'', -{''RabGGTaze''}-, ''geranilgeranil-difosfat,geranilgeranil-difosfat:protein-cistein geraniltransferaza'') je [[enzim]] sa sistematskim imenom ''geranilgeranil-difosfat:protein-cistein geraniltransferaza''.<ref>{{cite journal | title = Protein prenyltransferases |author1=Casey, P.J.  |author2=Seabra, M.C.  |lastauthoramp=yes |journal = J. Biol. Chem. |date = 1996 |volume = 271 |pages = 5289-5292 |pmid = 8621375}}</ref><ref>{{cite journal | title = Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases |author = Wilson, A.L., Erdman, R.A.,  Castellano, F. and Maltese, W.A. |journal = Biochem. J. |date = 1998 |volume = 333 |pages = 497-504 |pmid = 9677305}}</ref><ref>{{cite journal | title = Crystal structure of Rab geranylgeranyltransferase at 2.0 &Aring; resolution |author = Zhang, H., Seabra, M.C. and Deisenhofer, J. |journal = Structure |date = 2000 |volume = 8 |pages = 241-251 |pmid = 10745007}}</ref><ref>{{cite journal | title = Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate |author = Thom&auml;, N.H., Niculae, A., Goody, R.S. and Alexandrov, K. |journal = J. Biol. Chem. |date = 2001 |volume = 276 |pages = 48631-48636 |pmid = 11591706}}</ref><ref>{{cite journal | title = In vitro assembly, purification, and crystallization of the Rab geranylgeranyl transferase:substrate complex |author = Rak, A., Niculae, A., Kalinin, A., Thom&auml;, N.H., Sidorovitch, V., Goody, R.S. and Alexandrov, K. |journal = Protein Expr. Purif. |date = 2002 |volume = 25 |pages = 23-30 |pmid = 12071695}}</ref><ref>{{Cite book | chapter = Prenyl transfer and the enzymes of terpenoid and steroid biosynthesis | title = Comprehensive Biological Catalysis. A Mechanistic Reference |author=Gibbs, R.A. |year=1998|volume = 1 |pages=31-118 |editor = Sinnott, M. |edition  =  |publisher = Academic Press |location = San Diego, CA }}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: [[geranilgeranil difosfat]] + protein-cistein <math>\rightleftharpoons</math> -{S}--geranilgeranil-protein + [[difosfat]]

Ovaj enzim zajedno sa proteinskom farneziltransferazom ([[EC 2.5.1.58]]) i proteinskom geranilgeraniltransferazom tip I ([[EC 2.5.1.59]]) sačinjava proteinsku preniltransferaznu familiju enzima.

== Reference ==
{{reflist}}

== Литература ==
* {{Cite book |ref= harv|chapter = Prenyl transfer and the enzymes of terpenoid and steroid biosynthesis | title = Comprehensive Biological Catalysis. A Mechanistic Reference |author=Gibbs, R.A. |year=1998|volume = 1 |pages=31-118 |editor = Sinnott, M. |edition  =  |publisher = Academic Press |location = San Diego, CA }}

== Spoljašnje veze ==
* {{MeshName|Protein+geranylgeranyltransferase+type+II}}

{{Alkil i aril transferaze-lat}}
{{Enzimi-lat}}
{{Portal bar-lat|Molekularna i ćelijska biologija|Hemija}}

{{normativna kontrola}}

[[Категорија:ЕЦ 2.5.1]]