Изворни код странице GDP-Man:Man2GlcNAc2-PP-dolihol alfa-1,6-manoziltransferaza

{{Infobox Enzim-lat
| Name = GDP-Man:Man2GlcNAc2-PP-dolihol alfa-1,6-manoziltransferaza
| EC_number = 2.4.1.257
| CAS_number = 
| IUBMB_EC_number = 2/4/1/257
| GO_code = 
| image = 
| width = 
| caption =
}}
'''GDP-Man:Man2GlcNAc2-PP-dolihol alfa-1,6-manoziltransferaza''' ({{EC broj-lat|2.4.1.257}}, ''GDP-Man:Man2GlcNAc2-PP-Dol alfa-1,6-manoziltransferaza'', ''Alg2 manoziltransferaza'', ''ALG2 (gen)'', ''GDP-Man:Man1GlcNAc2-PP-dolihol manoziltransferaza'') je [[enzim]] sa sistematskim imenom ''GDP-D-manoza:D-Man-alfa-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-difosfodolihol alfa-6-manoziltransferaza''.<ref>{{cite journal | title = Biochemical characterization and membrane topology of Alg2 from ''Saccharomyces cerevisiae'' as a bifunctional &alpha;1,3- and  1,6-mannosyltransferase involved in lipid-linked oligosaccharide  biosynthesis |author = Kampf, M., Absmanner, B., Schwarz, M. and Lehle, L. |journal = J. Biol. Chem. |date = 2009 |volume = 284 |pages = 11900-11912 |pmid = 19282279}}</ref><ref>{{cite journal | title = ''In vitro'' evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis |author = O'Reilly, M.K., Zhang, G. and Imperiali, B. |journal = Biochemistry |date = 2006 |volume = 45 |pages = 9593-9603 |pmid = 16878994}}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: GDP--{D}--manoza + -{D-Man-alfa-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc}--difosfodolihol <math>\rightleftharpoons</math> GDP + -{D-Man-alfa-(1->3)-[D-Man-alfa-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc}--difosfodolihol

Biosinteza of asparaginom vezanih [[glikoprotein]]a koristi dolihil difosfat-vezani glikozilni donor.

== Reference ==
{{reflist}}

== Literatura ==
{{Литература}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{JencksCatalysisInChemistryAndEnzymology}}
{{Литература крај}}
== Spoljašnje veze ==
* {{MeshName|GDP-Man:Man2GlcNAc2-PP-dolichol+alpha-1,6-mannosyltransferase}}

{{Glikoziltransferaze-lat}}
{{Enzimi-lat}}
{{Portal bar-lat|Molekularna i ćelijska biologija|Hemija}}

{{normativna kontrola}}

[[Категорија:ЕЦ 2.4.1]]