Изворни код странице Defosfo-(reduktaza kinaza) kinaza

{{Infobox Enzim-lat
| Name = Defosfo-(reduktaza kinaza) kinaza
| EC_number = 2.7.11.3
| CAS_number = 72060-33-4
| IUBMB_EC_number = 2/7/11/3
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Defosfo-(reduktaza kinaza) kinaza''' ({{EC broj-lat|2.7.11.3}}, ''AMP-activirana kinaza'', ''AMP-activirana proteinska kinaza kinaza'', ''hidroksimetilglutaril koenzim A reduktaza kinaza kinaza'', ''hidroksimetilglutaril koenzim A reduktaza kinaza kinaza (fosforilacija)'', ''reduktazna kinaza'', ''reduktazna kinaza kinaza'', ''STK30'') je [[enzim]] sa sistematskim imenom ''ATP:defosfo-{(hidroksimetilglutaril-KoA reduktaza (NADPH)) kinaza} fosfotransferaza''.<ref>{{cite journal | title = Characterization and regulation of reductase kinase, a protein kinase that modulates the enzymic activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase |author = Beg, Z.H., Stonik, J.A. and Brewer, H.B., Jr. |journal = Proc. Natl. Acad. Sci. USA |date = 1979 |volume = 76 |pages = 4375-4379 |pmid = 291971}}</ref><ref>{{cite journal | title = Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme A reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation |author = Ingebritsen, T.S., Lee, H.-S., Parker, R.A. and Gibson, D.M. |journal = Biochem. Biophys. Res. Commun. |date = 1978 |volume = 81 |pages = 1268-1277 |pmid = 666819}}</ref><ref>{{cite journal | title = Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase |author = Beg, Z.H., Stonik, J.A. and Brewer, H.B., Jr. |journal = J. Biol. Chem. |date = 1985 |volume = 260 |pages = 1682-1687 |pmid = 3155737}}</ref><ref>{{cite journal | title = Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver | url = https://archive.org/details/sim_embo-journal_1990-08_9_8/page/2439 |author1=Clarke, P.R.  |author2=Hardie, D.G.  |lastauthoramp=yes |journal = EMBO J. |date = 1990 |volume = 9 |pages = 2439-2446 |pmid = 2369897}}</ref><ref>{{cite journal | title = Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion |author = Sato, R., Goldstein, J.L. and Brown, M.S. |journal = Proc. Natl. Acad. Sci. USA |date = 1993 |volume = 90 |pages = 9261-9265 |pmid = 8415689}}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: [[Аденозин-трифосфат|ATP]] + defosfo-{[hidroksimetilglutaril-KoA reduktaza (-{NADPH}-)] kinaza} <math>\rightleftharpoons</math> [[Аденозин-дифосфат|ADP]] + {[hidroksimetilglutaril-KoA reduktaza (-{NADPH}-)] kinaza}

Ovaj enzim se aktivira AMP-om i specifičan je za svoj supstrat.

== Reference ==
{{reflist}}

== Literatura ==
{{Литература}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
{{Литература крај}}
== Spoljašnje veze ==
* {{MeshName|Dephospho-(reductase+kinase)+kinase}}

{{Serin/treonin-specifične proteinske kinaze-lat}}
{{Enzimi-lat}}
{{Portal bar-lat|Molekularna i ćelijska biologija|Hemija}}

{{normativna kontrola}}

[[Категорија:ЕЦ 2.7.11]]