Изворни код странице B-karoten 15,15'-monooksigenaza

{{Infobox Enzim-lat
| Name = B-karoten 15,15'-monooksigenaza
| EC_number = 1.14.99.36
| CAS_number = 37256-60-3
| IUBMB_EC_number = 1/14/99/36
| GO_code = 
| image = 
| width = 
| caption =
}}
'''B-karoten 15,15'-monooksigenaza''' ({{EC broj-lat|1.14.99.36}}, ''beta-karotenska 15,15'-dioksigenaza'', ''karotenska dioksigenaza'', ''karotenska 15,15'-dioksigenaza'', ''-{BCMO1}- (gen)'') je [[enzim]] sa sistematskim imenom ''beta-karoten:kiseonik 15,15'-oksidoreduktaza (15,15'-epoksidacija, razgradnja veze)''.<ref>{{cite journal | title = Mechanism of the biosynthesis of vitamin A from &beta;-carotene |author = Goodman, D.S., Huang, H.S. and Shiratori, T. |journal = J. Biol. Chem. |date = 1966 |volume = 241 |pages = 1929-1932 |pmid = 5946623}}</ref><ref>{{cite journal | title = The enzymatic conversion of ''all''-''trans'' &beta;-carotene into retinal |author = Goodman, D.S., Huang, H.S., Kanai, M. and Shiratori, T. |journal = J. Biol. Chem. |date = 1967 |volume = 242 |pages = 3543-3554 |pmid = }}</ref><ref>{{cite journal | title = The reaction mechanism of the enzyme-catalysed central cleavage of &beta;-carotene to retinal |author = Leuenberger, M.G., Engeloch-Jarret, C. and Woggon, W.D. |journal = Angew. Chem. |date = 2001 |volume = 40 |pages = 2614-2616 |pmid = }}</ref><ref>{{cite journal | title = Substrate specificity of a recombinant chicken &beta;-carotene 15,15&prime;-monooxygenase that converts &beta;-carotene into retinal |author1=Kim, Y.S.  |author2=Oh, D.K.  |lastauthoramp=yes |journal = Biotechnol. Lett. |date = 2009 |volume = 31 |pages = 403-408 |pmid = 18979213}}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: [[beta-karoten]] + O<sub>2</sub> <math>\rightleftharpoons</math> 2 sve-trans retinal (sveukupna reakcija)
:(1a) beta-karoten + O<sub>2</sub> + -{AH}-<sub>2</sub> <math>\rightleftharpoons</math> beta-karoten 15,15' epoksid + -{H}-<sub>2</sub>O + A
:(1b) beta-karoten 15,15' epoksid + -{H}-<sub>2</sub>O <math>\rightleftharpoons</math> 15,15'-dihidroksi-beta-karoten
:(1c) 15,15'-dihidroksi-beta-karoten + A <math>\rightleftharpoons</math> 2 sve-trans retinal + -{AH}-<sub>2</sub>

Za rad ovog enzim su neophodne žučne soli i -{Fe}-(II).

== Reference ==
{{reflist}}

== Literatura ==
{{Литература}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
{{Литература крај}}
== Spoljašnje veze ==
* {{MeshName|Beta-carotene+15,15'-monooxygenase}}

{{Enzimi-lat}}
{{Portal bar-lat|Molekularna i ćelijska biologija|Hemija}}

{{normativna kontrola}}

[[Категорија:ЕЦ 1.14.99]]