Изворни код странице Arogenat dehidrogenaza (NADP+)

{{Infobox Enzim-lat
| Name = Arogenat dehidrogenaza (-{NADP}-<sup>+</sup>)
| EC_number = 1.3.1.78
| CAS_number = 64295-75-6
| IUBMB_EC_number = 1/3/1/78
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Arogenat dehidrogenaza (-{NADP}-<sup>+</sup>)''' ({{EC broj-lat|1.3.1.78}}, ''arogenatna dehidrogenaza (nespecifična)'', ''pretirozinska dehidrogenaza (nespecifična)'', -{''TyrAAT1'', ''TyrAAT2'', ''TyrAa''}-) je [[enzim]] sa sistematskim imenom ''-{L}--arogenat:-{NADP}-<sup>+</sup> oksidoreduktaza (dekarboksilacija)''.<ref>{{cite journal | title = Enzymology of L-tyrosine biosynthesis in corn (''Zea mays'') | url = https://archive.org/details/sim_phytochemistry_1981_20/page/1289 |author = Byng, G., Whitaker, R., Flick, C. and Jensen, R.A. |journal = Phytochemistry |date = 1981 |volume = 20 |pages = 1289-1292 |pmid = }}</ref><ref>{{cite journal | title = L-Tyrosine regulation and biosynthesis via arogenate dehydrogenase in suspension-cultured cells of ''Nicotiana silvestris'' Speg. et Comes | url = https://archive.org/details/sim_planta_1982-12_156_3/page/233 |author = Gaines, C.G., Byng, G.S., Whitaker, R.J. and Jensen, R.A. |journal = Planta |date = 1982 |volume = 156 |pages = 233-240 |pmid = }}</ref><ref>{{cite journal | title = Purification and kinetic analysis of the two recombinant arogenate dehydrogenase isoforms of ''Arabidopsis thaliana'' |author1=Rippert, P.  |author2=Matringe, M.  |lastauthoramp=yes |journal = Eur. J. Biochem. |date = 2002 |volume = 269 |pages = 4753-4761 |pmid = 12354106}}</ref><ref>{{cite journal | title = A core catalytic domain of the TyrA protein family: arogenate dehydrogenase from ''Synechocystis'' |author = Bonner, C.A., Jensen, R.A., Gander, J.E. and Keyhani, N.O. |journal = Biochem. J. |date = 2004 |volume = 382 |pages = 279-291 |pmid = 15171683}}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: -{L}--arogenat + -{NADP}-<sup>+</sup> <math>\rightleftharpoons</math> -{L}--tirozin + -{NADPH}- + -{CO}-<sub>2</sub>

Za razliku od [[EC 1.3.1.43]] (arogenat dehidrogenaze) i [[EC 1.3.1.79]] [arogenat dehidrogenaze (-{NAD(P)}-<sup>+</sup>)], ovaj enzim enzim koristi samo -{NADP}-<sup>+</sup>. Enzim iz -{''[[Synechocystis]]'' sp. PCC 6803}- i izoforme -{TyrAAT1}- ne može da koristi prefenat kao supstrat, dok izoforma -{TyrAAT2}- može da ga koristi, mada veome slabo.

== Reference ==
{{reflist}}

== Literatura ==
{{Литература}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{JencksCatalysisInChemistryAndEnzymology}}
{{Литература крај}}
== Spoljašnje veze ==
* {{MeshName|Arogenate+dehydrogenase+(NADP+)}}

{{CH-CH oksidoreduktaze-lat}}
{{Enzimi-lat}}
{{Portal bar-lat|Molekularna i ćelijska biologija|Hemija}}

{{normativna kontrola}}

[[Категорија:ЕЦ 1.3.1]]