Изворни код странице 18S rRNK (adenin1779-N6/adenin1780-N6)-dimetiltransferaza

{{Infobox Enzim-lat
| Name = 18-{S}- rRNK (adenin<sup>1779</sup>--{N}-<sup>6</sup>/adenin<sup>1780</sup>--{N}-<sup>6</sup>)-dimetiltransferaza
| EC_number = 2.1.1.183
| CAS_number = 
| IUBMB_EC_number = 2/1/1/183
| GO_code = 
| image = 
| width = 
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}}
'''18-{S}- rRNK (adenin<sup>1779</sup>--{N}-<sup>6</sup>/adenin<sup>1780</sup>--{N}-<sup>6</sup>)-dimetiltransferaza''' ({{EC broj-lat|2.1.1.183}}, ''18-{S}- rRNK dimetilaza -{Dim1p'', ''Dim1p'', ''ScDim1'', ''m2(6)A}- dimetilaza'', -{''KIDIM1''}-) je [[enzim]] sa sistematskim imenom ''-{S}--adenozil--{L}--metionin:18-{S}- rRNK (adenin<sup>1779</sup>--{N}-<sup>6</sup>/adenin<sup>1780</sup>--{N}-<sup>6</sup>)-dimetiltransferaza''.<ref>{{cite journal | title = The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast |author = Lafontaine, D., Vandenhaute, J. and Tollervey, D. |journal = Genes Dev. |year=1995|volume = 9 |pmid = 7590228|pages=2470-2481}}</ref><ref>{{cite journal | title = Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis | url = https://archive.org/details/sim_molecular-and-cellular-biology_1998-04_18_4/page/2360 |author = Lafontaine, D.L., Preiss, T. and Tollervey, D. |journal = Mol. Cell Biol. |year=1998|volume = 18 |pmid = 9528805|pages=2360-2370}}</ref><ref>{{cite journal | title = Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases |author = Pulicherla, N., Pogorzala, L.A., Xu, Z., O'Farrell, H.C., Musayev, F.N., Scarsdale, J.N., Sia, E.A., Culver, G.M. and Rife, J.P. |journal = J. Mol. Biol. |year=2009|volume = 391 |pmid = 19520088|pages=884-893}}</ref><ref>{{cite journal | title = The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3′-terminal loop of 18 S rRNA is essential in yeast |author = Lafontaine, D., Delcour, J., Glasser, A.L., Desgres, J. and Vandenhaute, J. |journal = J. Mol. Biol. |year=1994|volume = 241 |pmid = 8064863|pages=492-497}}</ref><ref>{{cite journal | title = Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution |author = O'Farrell, H.C., Pulicherla, N., Desai, P.M. and Rife, J.P. |journal = RNA |year=2006|volume = 12 |pmid = 16540698|pages=725-733}}</ref> Ovaj enzim [[Катализа|katalizuje]] sledeću [[hemijska reakcija|hemijsku reakciju]]

: 4 -{S}--adenozil--{L}--metionin + [[adenin]]<sup>1779</sup>/adenin<sup>1780</sup> u 18-{S}- rRNK <math>\rightleftharpoons</math> 4 -{S}--adenozil--{L}--homocistein + -{N}-<sup>6</sup>-dimetiladenin<sup>1779</sup>/-{N}-<sup>6</sup>-dimetiladenin<sup>1780</sup> u 18-{S}- rRNK

-{DIM1}- učestvuje u pre-rRNK transformacijama.

== Reference ==
{{reflist}}

== Literatura ==
{{Литература}}
* {{PriceEnzymology3rd}}
* {{TooneAdvancesInEnzymology}}
* {{Branden ProteinStructure2nd}}
* {{SegelEnzymeKinetics}}
* {{JencksCatalysisInChemistryAndEnzymology}}
{{Литература крај}}
== Spoljašnje veze ==
* {{MeshName|18S+rRNA+(adenine1779-N6/adenine1780-N6)-dimethyltransferase}}

{{Jednougljenične transferaze-lat}}
{{Enzimi-lat}}
{{Portal bar-lat|Molekularna i ćelijska biologija|Hemija}}

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[[Категорија:ЕЦ 2.1.1]]